Frequently Asked Questions

Browse the site for the most frequently asked questions we receive.

Your DNA can tell a lot about you and your health. For example, it can tell you why you are not losing weight, whether you should add more supplements to your diet, what kind of exercise is right for you, and more. Your DNA will even reveal if you are likely to develop certain diseases such as diabetes, high blood pressure, thyroid disorders, hereditary diseases and much more. Overall, a DNA test will uncover a wide variety of important insights about your health. Unravel and understand the mystery of your unique genes and begin your personal nutrition and
health journey.

This test is suitable for anyone who wants to understand how their DNA affects their overall wellbeing, from physical to mental health.

A DNA profile can provide you with detailed valuable information about your genetic traits based on the diet and lifestyle plan that is best for you.

All we require is a cheek sample, for which we will provide you with a swab kit. Your DNA will be extracted from the white blood cells and inner cheek skin cells found in your mouth sample.

The results of your DNA genotyping are based on thousands of published research articles that demonstrate relevant effects on diet and fitness with easy-to-implement lifestyle changes. Genotyping examines specific points in your DNA and then identifies their variations. These variations are what make you unique. 

In selecting these specific points, we target variations known to be associated with important dietary habits, traits, and diseases. Genotyping is a great way to understand how your DNA can affect your daily lifestyle.

The genotyping process has a validated accuracy of 99.9% and we process all test samples in our laboratory in Malaysia.

All DNA categories tested are backed by rigorous research from leading scientists and research institutes around the world.

Carrier screening is a type of genetic test that can be used to find out if you carry a mutation for a particular genetic disease that could be passed on to your child. Many of us are carriers of multiple genetic diseases, usually with no symptoms and no effect on our health. However, if two people are carriers of the same inherited disease and have children together, there is a 1 in 4 chance that the child who inherits two mutated genes from both parents may have the inherited disease. Usually, the diseases detected during carrier screening are very serious and lead to death or severe disabilities in early childhood. Therefore, carrier screening helps to reduce this risk.

Examples of genetic diseases range from deafness to more severe conditions such as Sickle Cell Disease (1), which can significantly affect a child’s quality of life and reduce life expectancy.

  • Sickle Cell Disease is an inherited blood disorder that affects a major component of red blood cells, haemoglobin, and causes red blood cells to have a stiff, sickle-shaped appearance resembling a sickle. An adequate amount of red blood cells and haemoglobin is necessary to efficiently deliver oxygen to all the cells in your body. As the sickle-shaped blood cells die prematurely, the poor supply of oxygen to the body makes the sufferer feel weak and tired. These sickled cells can also get stuck in small blood vessels, blocking blood flow and causing serious medical complications such as tissue deterioration.

Many of us are carriers of hereditary diseases and simply do not know it. More than 80% of children with inherited diseases are born to parents who do not know they carry the variant. 

For many inherited diseases, such as Sickle Cell Disease (1) and Cystic Fibrosis (2), there may be no family history on either side of the parents. This is because a single copy of a mutation does not usually cause symptoms, so many people are “carriers” of inherited diseases without ever knowing it. Almost all of these diseases are inherited in an autosomal recessive manner, meaning that an affected child must inherit one copy of the gene with the disease-causing mutation from each parent. So, if two people who are carriers of the same disease have children together, each child has a 1 in 4 chance of being born with the disease.

Individually, inherited diseases may be rare. Overall, however, there is at least a 1 in 3 chance that you will be a carrier of at least one of the diseases tested for. This is much higher than the incidence of Down syndrome. Knowing your risk profile before or in the early stages of pregnancy will allow you to calmly weigh your options with your healthcare provider and make a decision.

  • Sickle Cell Disease is an inherited blood disorder that affects a major component of red blood cells, haemoglobin, and causes red blood cells to have a stiff, sickle-shaped appearance resembling a sickle. The sickle-shaped blood cells die prematurely, leaving sufferers feeling weak and tired. These sickled cells can also get stuck in small blood vessels, blocking blood flow and causing serious medical complications such as tissue deterioration.
  • Cystic fibrosis is a serious disease that can affect different parts of the body such as the lungs, intestines, pancreas, etc. This disease is caused by a gene called CFTR. When CFTR does not function well due to a gene mutation, mucus can become thick and sticky, clogging the airways and intestines. Healthy mucus is needed to clear germs, and germs can get trapped in tough mucus. This can lead to frequent lung infections and death in childhood or early adulthood.

Your DNA will be tested in our laboratory here in Malaysia, Synapse Sdn Bhd. The laboratory is equipped with the latest next generation sequencing and genotyping technologies and is staffed by a panel of experienced geneticists, pathologists, computer scientists and consultants.

Your report will be simplified so that you can easily understand it. We also offer consultation services with an experienced genetic counsellor.

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Unlock a wealth of infomation about yourself throught your DNA.

Disclaimer: Please note that this report solely relies on your genetic information and does not consider other shared details. It examines specific variants associated with certain conditions but does not encompass all variants. Other associated markers or variants may not be screened. The report is not diagnostic and should not be treated as such. It reveals your genetic predisposition to health conditions. High or low risk does not indicate presence or absence of conditions; development depends on genetic predisposition, lifestyle choices, exposure, and more. The report helps assess genetic health status and make informed choices. Genotype determination assumes diploid DNA samples, and atypical genome content may affect results. Consult a doctor before considering recommendations. Synapse Laboratory is not liable for any damages resulting from the service or report.